Many patients with CAH lack cortisol and have too much androgen. Patients with CAH are missing one of the enzymes needed to produce certain steroid hormones including cortisol, aldosterone and androgens – encompassing sex hormones such as testosterone. If not appropriately treated, adrenal insufficiency symptoms can include severe abdominal pain, extreme weakness, low blood pressure, kidney failure or shock.Ĭongenital Adrenal Hyperplasia: Congenital adrenal hyperplasia (CAH) is characterized by nonmalignant growth of the adrenal glands. It also controls blood pressure and can impact the immune system. Cortisol helps break down fats, proteins and carbohydrates in the body.
Our endocrinology specialists provide comprehensive treatment for a full range of adrenal gland disorders, including:Īdrenal Insufficiency: Also known as Addison’s disease, patients are diagnosed with adrenal insufficiency when there is a deficient supply of the cortisol hormone. These conditions can be caused by genetic mutations, certain types of tumors, infections, medications or a problem that originates in another gland such as the pituitary. When the adrenal glands produce too much or too little of certain hormones, a disorder is present. Sex hormones are also produced in the cortex. The adrenal cortex surrounds the medulla and produces hormones such as cortisol hormones, which regulates the body’s response to stress and illness and aldosterone to maintain fluid and electrolyte balance. The medulla is in the center of the gland and is responsible for producing epinephrine and norepinephrine – otherwise known as adrenaline. Understanding Adrenal Gland DisordersĪdrenal glands are located at the top of both kidneys and produce hormones that all people must have to stay alive. When questions arise, we are available 24/7 to help guide your child and family in the right direction. Our multidisciplinary team includes board-certified and fellowship-trained pediatric endocrinologists, social workers, nurses, dieticians and other specialists who work collaboratively with patients and families to ensure you have the best information available to make the most informed decisions. It’s part of our ongoing commitment to ensuring all patients realize the best outcome for a happy, healthy life.
Our dedicated team of nationally-recognized endocrinologists is leading the way to advance new guidelines for conditions like adrenal insufficiency and other rare disorders. The group of pediatric endocrinology, diabetes and metabolism specialists at University Hospitals Rainbow Babies & Children’s not only offers the latest expertise in adrenal gland disorders, but sets a higher standard of care.
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